Dr. Gaurav Jerath, PhD

About

I started my research journey in the fields of Bioinformatics and Computational Biology. In later years, my work developed in the fields of protein biophysics, biochemistry and chemical biology. I earned my doctorate from the department of Biosciences and Bioengineering at Indian Institute of Technology Guwahati. Post PhD, I founded a start-up to work on the development of applications for peptide-based biomolecules for prevention and treatment of infectious and non- infectious diseases. As a founder, I was successfully able to lead a team of researchers through multiple quests and challenges. At present, the start-up is funded by the Biotechnology Industry Research Assistance Council (BIRAC), Govt. of India.

Background

• 2019 PhD in Biosciences and Bioengineering, Indian Institute of Technology Guwahati
• 2012 M.Tech. Biotechnology (Honors), School of Biotechnology, Lovely Professional University
• 2010 B.Tech. Biotechnology (Honors), Rajasthan Technical University

Honours and Awards

• 2013 Academic Honor for University Topper, Lovely Professional University
• 2012 CSIR-UGC National Eligibility Test, All India Rank: 53
• 2012 Graduate Aptitude Test Examination in Biotechnology, All India Rank: 452
• 2011 CSIR-UGC National Eligibility Test, All India Rank: 35
• 2010 CSIR-UGC National Eligibility Test, All India Rank: 141

Research Group Overview

• My research is focussed on the development of biomolecular therapeutics. At our lab, we are working on development of biomolecular drug delivery vectors and drug-like molecules. The other segment of the research comprises of the use of Network Biology and Combinatorial Therapy for the development of Personalized and Network Medicine. Our target disease models include antimicrobial resistance, Infectious diseases, Metabolic disorders, Alzheimer’s and Cancers

Publications

• Gaurav Jerath, R. Goyal, V. Trivedi, T. Santhoshkumar, V. Ramakrishnan, Syndiotactic peptides for targeted delivery. Acta Biomaterialia 87, 130-139 (2019). Impact Factor: 10.633.
• Gaurav Jerath, P. K. Hazam, S. Shekhar, V. Ramakrishnan, Mapping the geometric evolution of protein folding motor. PloS ONE 11, e0163993 (2016). Impact Factor: 3.752
• Gaurav Jerath, R. Goyal, V. Trivedi, T. R. Santhoshkumar, V. Ramakrishnan, Conformationally constrained peptides for drug delivery. Journal of Peptide Science 26, e3244 (2020). Impact Factor: 2.455
• R. Goyal, Gaurav Jerath, A. Chandrasekharan, E.R, Puppala, V.G.M. Naidu, T. R. Santhoshkumar, V. Ramakrishnan, Geometry Encoded Functional Programming of Tumor Homing Peptides for Targeted Drug Delivery, Journal of Controlled Release 333, 16-27 (2021). Impact Factor: 11.467.
• A. Rai, V. Kumar, Gaurav Jerath, C. Kartha, V. Ramakrishnan, Mapping drug-target interactions and synergy in multi-molecular therapeutics for pressure-overload cardiac hypertrophy. NPJ Systems Biology and Applications 7, 1-11 (2021). Impact Factor: 4.671.