Dr. Arun Bandyopadhyay

Dr. Arun Bandyopadhyay

Director

M.Tech, Ph.D, FAScT, FNASc, FNA

About

Background

RESEARCH INTEREST

  • Biomarker for Risk Assessment of Cardiovascular Diseases
  • Inflammation in  Atherosclerosis
  • Mitochondrial dynamics and biogenesis in cardiac hypertrophy
  • Therapeutics for the Management of Respiratory Diseases

HOBBIES

  1. Swimming 
  2. Running
  3. Bicycling
  4. Badminton 

Honours and Awards

  • Fellow of the Indian National Science Academy, FNA
  • Fellow of the National Academy of Sciences, FNASc
  •  Fellow of West Bengal Academy of Science and Technology (WAST)
  •  Sir C. V. Raman Research Fellowship award by CSIR
  •  Recipient of Jimmie Dod Memorial award for Best poster Presentation in International Congress of Comparative Endocrinology, Yokohama, Japan in 1997
  • Life Member of Society of Biological Chemists (I)      
  •  Life Member of Proteomic Society of India.

Research Group Overview

ALUMNI (CSIR-IICB)

    1. Dr. Ritu Gautam
    2. Dr. Devasmita Chakravarty
    3. Dr. Aleepta Guha Ray
    4. Dr. Dibyanti Mukherjee
    5. Dr. Apabrita Ayan Das
    6. Dr. Kamalika Roy Choudhury
    7. Dipak Kar
    8. Dr. Vivek Chander
    9. Dr. Tanima Banerjee
    10. Dr. Somaditya Mukherjee
    11. Dr. Shantanu Dutta
    12. Dr. Aditya Konar
    13. Dr. Priyam Banerjee
    14. Dr. Sreerupa Ghose Roy
    15. Dr. Sumita Mishra
    16. Dr. Priyanka De
    17. Dr. Goutam Ghosh
    18. Dr. Kakali De

PRODUCT

Prototype for Detection of Rheumatic Heart Disease

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Patents

Sl no. Title Patent no/Filing no. Translational Research Contributions
1 TRIAZINE-ARYL-BIS-INDOLES AND PROCESS FOR PREPARATION THEREOF Patent no. 9085559

Granted: 21/07/2015

 Novel PDE4 inhibitor targeted for lung disease therapy as a bronchidilator. Preclinical lab level validations done
2 Inhibitors of IL-4 and IL-5 for the treatment of bronchial asthma.

 

 

 Patent no. 9302967

Granted 05/04/2016

 

 Novel anti-inflammatory compound, targeted for combination  therapy with PDE4 inhibitor. Preclinical lab level validations done
3 A molecule from herbal origin for the treatment of bronchial asthma Appl No. 0267DEL2011, Prov Filing Dt. 4/2/2011 A plant source of PDE 4 inhibitor. Alternate medicine for asthma and COPD

Publications

  1. Sengupta S, Abhinav N, Singh S,  Dutta J, Mabalirajan U, Kaliyamurthy K, Mukherjee PK, Jaisankar P and Bandyopadhyay A. Standardised Sonneratia apetala Buch.-Ham. fruit extract inhibits human neutrophil elastase and attenuates elastase-induced lung injury in mice. Front. Pharmacol. 2022. 13:1011216. DOI 10.3389/fphar.2022.1011216.
  2. Sengupta S, Reddy JR , Rajesh N, Jaiswal A, Mabalirajan, U, Palakodety RK, Mukherjee P, Bandyopadhyay, A. Novel benzoxazinone derivative as potent human neutrophil elastase inhibitor: Potential implications in lung injury. Eur J  Pharm, 2022, 931: 175187. DOI 10.1016/j.ejphar.2022.175187.
  3. Kumari R, Guha Ray A, Mukherjee D, Chander V, Kar D, Kumar US, Bharadwaj PVP D, Banerjee SK, Konar A and Bandyopadhyay A. Down regulation of PTEN promotes autophagy via concurrent reduction in apoptosis in cardiac hypertrophy in PPAR α-/- Mice. Front Card Vasc Med 2022, 9:798639. DOI 10.3389/fcvm.2022.798639.
  4. Chakravarty D, Guha Ray A, Chander, V, Mabalirajan U,  Mondal PC,  Siddiqui KN, Sinha BP, Konar, A and Bandyopadhyay A. Systemic deficiency of vitronectin is associated with aortic inflammation and plaque progression in ApoE-Knockout mice. FASEB BioAdvances. 2021;00:1–17.  DOI: 10.1096/fba.2021-00108.
  5. Mukherjee D, Chander V and Bandyopadhyay A. PARIS-DJ-1 Interaction Regulates Mitochondrial Functions in Cardiomyocytes which is Critically Important in Cardiac Hypertrophy. Mol Cell Biol 2021, 41 (1): e00106-20.
  6. Guha Ray A, Roy Choudhury K, Chakraborty S, Chakravarty D, Chander V, Jana B, Siddiqui KN and Bandyopadhyay A. Novel Mechanism of Cholesterol Transport by ABCA5 in Macrophages and Its Role in Dyslipidemia. J Mol Biol, 2020, 432,4922-4941.
  7. Das AA, Roychoudhury K, Jagadeeshaprasad M G, Kulkarni MJ, Mondal PC and Bandyopadhyay A. Proteomic Analysis Detects Dysregulated Reverse Cholesterol Transport in Human Subjects with ST-Segment Elevation Myocardial Infarction. J Proteomics. 2020, 30,103796.
  8. Das AA, Chakravarty D, Bhunia D, Ghosh S,  Mandal PC, Siddiqui KN  and Bandyopadhyay A. Elevated level of circulatory sTLT1 induces inflammation through SYK/MEK/ERK signaling in coronary artery disease. Clin Science, 2019, 133 (22), 2283-2299.
  9. Kar, D and Bandyopadhyay A. Targeting Peroxisome Proliferator Activated Receptor α (PPAR α) for the Prevention of Mitochondrial Impairment and Hypertrophy in Cardiomyocytes. Cell Phyiol. Biochem, 2018, 49, 245-259.
  10. Mastorci F , Vassalle C, Chatzianagnostou K , Marabotti C , Siddiqui K , Eba AO, Sidi Mhamed SA , Bandyopadhyay A , Nazzaro MS , Passera M and Pingitore A. Undernutrition and Overnutrition Burden for Diseases in Developing Countries: The Role of Oxidative Stress Biomarkers to Assess Disease Risk and Interventional Strategies. Antioxidant, 2017, 6, 41
  11. Mukherjee S and Bandyopadhyay A. Proteomics in India: the clinical aspect. Clin Proteomics 2016, 13:21.
  12. Banerjee et al. A novel triazine-aryl-bis-indole derivative inhibits both phosphodiesterase IV and expression of cell adhesion molecules. RSC Adv., 2015, 5, 70271–70281
  13. Banerjee, P, Chander V, Bandyopadhyay, A. Balancing functions of annexin A6 maintain equilibrium between hypertrophy and apoptosis in cardiomyocytes. Cell Death Dis (NPG). 2015;6:e1873. doi: 10.1038/cddis.2015.231
  14. Banerjee P and Bandyopadhyay A. Cytosolic dynamics of annexin A6 triggers feedback regulation of hypertrophy via atrial natriuretic peptide in cardiomyocytes. J.Biol.Chem. 2014, 289, 5371-5385.
  15. Banerjee T, Mukherjee, S, Ghosh, S, Biswas M, Dutta S, Pattari S, Chatterjee S, Bandyopadhyay A. Clinical Significance of Markers of Collagen Metabolism in Rheumatic Mitral Valve Disease. PLOS ONE. 2014, 9: e9052

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